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How to Make IVF Successful The First Time?

The journey towards conception can be a difficult one for those struggling with infertility. In vitro fertilization (IVF) is an assisted reproductive technology that offers hope for many couples struggling to conceive.

However, the success rate of IVF can be impacted by several factors, leading to multiple failed attempts. 

If you’ve experienced multiple unsuccessful rounds of IVF, or you’re planning your first one, you may be wondering how to make it successful the first time around.

In this article, we’ll discuss some tips to increase your chances of IVF success.

How to Make IVF Successful The First Time?

What is IVF?

IVF is a process in which an egg is fertilized with sperm outside the body in a laboratory. Once the embryo is formed, it is transferred to the uterus. Several factors such as age, fertility history, and the quality of the embryo can impact the success rate of IVF. 

While the average success rate of IVF is 30% – 40%, factors such as age, health, and other medical and environmental factors can affect the success rate.

Tips to Increase the Chance of Your IVF Success Rate

Stress Management

The IVF process can be stressful, and stress can negatively impact the chances of success. Therefore, it’s essential to manage stress during the IVF cycle. Here are some tips for stress management:

  1. Exercise: Regular exercise has been shown to reduce stress levels and improve overall well-being.
  2. Mind-body techniques: Practices like yoga, meditation, and deep breathing can significantly reduce stress and improve mental health.
  3. Seek emotional support: The IVF journey can be emotionally taxing. Seek emotional support from friends, family, or professional counseling to help you navigate the emotional journey.

Lifestyle Changes

Lifestyle modifications can help increase the chances of a successful outcome during IVF. Here are some lifestyle changes that you can make:

  1. Quit Smoking: Smoking is known to impact fertility negatively. Therefore, quitting smoking can increase the chances of success.
  2. Avoid Alcohol: Like smoking, alcohol consumption can decrease the effectiveness of IVF treatment. 
  3. Maintain a Healthy Weight: Being overweight or underweight can negatively impact fertility. Maintaining a healthy weight can increase the chances of success.

Dietary Factors

Dietary factors can influence an individual’s fertility. Here are some dietary modifications that you can make to increase the chances of success:

  1. Take a folic acid supplement: Folic acid plays a crucial role in the development of the embryo. Taking a folic acid supplement can improve your chances of a successful outcome. But, we recommend consulting your doctor than self medication.
  2. Eat a Healthy Diet: Eating a diet rich in fruits, vegetables, and whole grains can improve overall health and fertility.
  3. Limit Caffeine Intake: High caffeine intake has been linked to lower fertility. Limiting caffeine intake can improve the chances of success.

IVF Protocol

The IVF protocol chosen by your fertility specialist in Bangalore can significantly influence the chances of success during the first cycle of IVF. Here are some important factors to consider:

  1. Use of Frozen Embryos: Using frozen embryos during the first cycle rather than fresh embryos can increase the chances of success.
  2. Day 5 Embryo Transfer: Transferring embryos on Day 5, rather than Day 2 or Day 3, can improve the chances of success.
  3. Pre-implantation Genetic Screening (PGS): PGS can help identify embryos that are less likely to result in pregnancy and increase the chances of selecting the best embryo for transfer.

Choose the Right IVF Clinic

It is one of the most crucial steps to increase the chances of success during the first cycle of IVF treatment. It’s essential to do thorough research, seek recommendations, and check the clinic’s track record of success.

When choosing the best IVF clinic in Bangalore, consider the clinic’s experience in handling complex infertility cases, the qualifications and experience of the fertility specialist and embryologists, the quality of laboratory standards and equipment used, and the clinic’s patient care and support services.

Reading reviews and testimonials from former patients can also provide valuable insights into the clinic’s expertise and patient care. Additionally, consider the clinic’s location, ease of accessibility, and affordability.

Follow the medication regimen prescribed

IVF medication regimen can be overwhelming due to the number of hormones and medications that need to be administered. It is vital to follow the medication regimen as instructed by your fertility specialist to ensure optimal results.

Skipping doses or not taking the right dose can negatively impact the chances of success. Patients must be diligent in taking their medications and adhere to their prescribed schedule. Set reminders or alarms to keep track of medication schedules and ensure timely administration.

Moreover, some medications have specific timing requirements that must be adhered to strictly.

The fertility medication protocol is critical as it helps stimulate the development of multiple eggs, which are then retrieved and fertilized to create embryos. Therefore, it is essential to follow the medication regimen to have the best chance of success during an IVF cycle.

Understand your menstrual cycle

Understanding the menstrual cycle is an essential step in an IVF treatment in Bangalore. It helps to identify the most fertile period when conception is most likely to occur.

Keep track of your menstrual cycle, including the start date, duration of the cycle, and the length of your period. There are several apps available for tracking menstrual cycles and identifying fertile periods.

In a standard menstrual cycle, ovulation typically occurs between days 11 to 14, where fertility is highest. During the ovulation period, the egg is released from the ovary and travels down the fallopian tube, where it can be fertilized by sperm. It is recommended to use ovulation predictor kits to detect when ovulation is about to occur.

One should schedule their IVF procedures around the most fertile period to maximize the chances of conception. Additionally, monitoring the menstrual cycle can help detect any irregularities that may require medical attention.


The decision to undergo IVF is a significant one, and multiple failed IVF attempts can be emotionally and physically draining. It’s important to recognize that no single factor can guarantee success. However, by following these tips, you can increase your chances of success during your first cycle of IVF. 

At Dr. Shilpa GB Fertility Clinic, we offer comprehensive support and guidance to help couples maximize their chances of successful IVF. If you have any questions or want to know more about our services, please get in touch with us. We’re committed to helping you start or grow your family in the best way possible.